Why should I check the lug nuts 50-100 miles after the wheels have been installed?

When dual wheels are installed the bolted joint that encompasses the stud, hub/drum, wheels, and fastener is going to flex as soon as the axle is loaded. The initial flexing results in joint settling that can cause the wheels to become loose. By checking the lug nuts after the first 50-100 miles of service, any joint settling that has occurred can be corrected by tightening or replacing the fasteners.